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Human LRP8 protein

SKU
Name
Human LRP8 protein
Size
50 ug
Price
$398.00
Qty

Human LRP8 protein

Description
Recombinant protein from the full-length sequence of homo sapiens LDL receptor related protein 8 (LRP8), transcript variant 3 (NM_017522), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_017522; NP_059992; UniProt#: Q14114; GeneID: 7804;
Synonyms
APOER2; HSZ75190; LRP-8; MCI1
Molecular Weight
74.4 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011]

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