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Human RUNX1 protein

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Human RUNX1 protein
Size
Price
$398.00
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Human RUNX1 protein

Description
Recombinant protein from the full-length sequence of homo sapiens runt related transcription factor 1 (RUNX1), transcript variant 2 (NM_001001890), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_001001890; NP_001001890; UniProt#: Q01196; GeneID: 861;
Synonyms
AML1; AML1-EVI-1; AMLCR1; CBFA2; EVI-1; PEBP2aB
Molecular Weight
48.6 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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