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Human RUNX1 protein

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Human RUNX1 protein
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$398.00
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Human RUNX1 protein

Description Recombinant protein from the full-length sequence of homo sapiens runt related transcription factor 1 (RUNX1), transcript variant 2 (NM_001001890), with a His tag.
Host Human cells
RefSeq Link NM_001001890; NP_001001890; UniProt#: Q01196; GeneID: 861;
Synonyms AML1; AML1-EVI-1; AMLCR1; CBFA2; EVI-1; PEBP2aB
Molecular Weight 48.6 kDa
Purity >90% by SDS-PAGE gel and Coomassie Blue staining
Applications Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg)
Background Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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