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Human CTAG2 protein

SKU
Name
Human CTAG2 protein
Size
50 ug
Price
$398.00
Qty

Human CTAG2 protein

Description
Recombinant protein from the full-length sequence of homo sapiens cancer/testis antigen 2 (CTAG2), transcript variant 1 (NM_172377), with a His tag.
Host
Human cells
Tags
His
RefSeq Link
NM_172377; NP_758965; UniProt#: O75638; GeneID: 30848;
Synonyms
CAMEL; CT2; CT6.2; CT6.2a; CT6.2b; ESO2; LAGE-1; LAGE2B
Molecular Weight
18.1 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013].

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