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Human CYP2C9 protein

SKU
Name
Human CYP2C9 protein
Size
50 ug
Price
$398.00
Qty

Human CYP2C9 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens cytochrome P450 family 2 subfamily C member 9 (CYP2C9) (NM_000771), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_000771; NP_000762; UniProt#: P11712; GeneID: 1559;
Synonyms
CPC9; CYP2C; CYP2C10; CYPIIC9; P450IIC9
Molecular Weight
55.4 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by RIXXXXXN. The enzyme is known to metabolize many xenobiotics, including PHXXXXXXN, TOXXXXXXXXE, ibuprofen and S-WAXXXXXN. Studies identifying individuals who are poor metabolizers of PHXXXXXXN and TOXXXXXXXXE suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008].

SDS-Page Image
Fig 1 : SDS-Page Image
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