×
Login

Human EIF2S1 protein

SKU
Name
Human EIF2S1 protein
Size
Price
$398.00
Qty

Human EIF2S1 protein

Description
Recombinant protein from the full-length sequence of homo sapiens eukaryotic translation initiation factor 2 subunit alpha (EIF2S1) (NM_004094), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_004094; NP_004085; UniProt#: P05198; GeneID: 1965;
Synonyms
EIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A
Molecular Weight
35.9 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010].

Contact Us
View Storefront

Related Products


There's no citations at this moment.


There's no FAQs at this moment.


There's no reviews at this moment.