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Human COL8A2 protein

SKU
Name
Human COL8A2 protein
Size
50 ug
Price
$398.00
Qty

Human COL8A2 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens collagen type VIII alpha 2 chain (COL8A2), transcript variant 1 (NM_005202), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_005202; NP_005193; UniProt#: P25067; GeneID: 1296;
Synonyms
FECD; FECD1; PPCD; PPCD2
Molecular Weight
67.2 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

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