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Human EIF2AK4 protein

SKU
Name
Human EIF2AK4 protein
Size
50 ug
Price
$398.00
Qty

Human EIF2AK4 protein

Description
Recombinant protein from the full-length sequence of homo sapiens eukaryotic translation initiation factor 2 alpha kinase 4 (EIF2AK4) (NM_001013703), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_001013703; NP_001013725; UniProt#: Q9P2K8; GeneID: 440275;
Synonyms
GCN2; PVOD2
Molecular Weight
186.7 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014].

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