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Human NUMA1 protein

SKU
Name
Human NUMA1 protein
Size
50 ug
Price
$398.00
Qty

Human NUMA1 protein

Description
Recombinant protein from the full-length sequence of homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), transcript variant 1 (NM_006185), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_006185; NP_006176; UniProt#: Q14980; GeneID: 4926;
Synonyms
NMP-22; NUMA
Molecular Weight
238.1 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

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