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Human DNM1L protein

SKU
Name
Human DNM1L protein
Size
50 ug
Price
$398.00
Qty

Human DNM1L protein

Description
Recombinant protein from the full-length sequence of Homo sapiens dynamin 1 like (DNM1L), transcript variant 1 (NM_012062), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_012062; NP_036192; UniProt#: O00429; GeneID: 10059;
Synonyms
DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV
Molecular Weight
81.7 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013].

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