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Human VAV3 protein

SKU
Name
Human VAV3 protein
Size
50 ug
Price
$398.00
Qty

Human VAV3 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens vav guanine nucleotide exchange factor 3 (VAV3), transcript variant 2 (NM_001079874), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_001079874; NP_001073343; UniProt#: Q9UKW4; GeneID: 10451;
Synonyms
FLJ40431
Molecular Weight
32.4 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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