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Human PTPRN protein

SKU
Name
Human PTPRN protein
Size
50 ug
Price
$398.00
Qty

Human PTPRN protein

Description
Recombinant protein from the full-length sequence of Homo sapiens protein tyrosine phosphatase receptor type N (PTPRN), transcript variant 1 (NM_002846), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_002846; NP_002837; UniProt#: Q16849; GeneID: 5798;
Synonyms
IA-2; IA-2/PTP; IA2; ICA512; R-PTP-N
Molecular Weight
105.8 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010].

SDS-Page Image
Fig 1 : SDS-Page Image
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