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Human GSDMB protein

SKU
Name
Human GSDMB protein
Size
50 ug
 

Human GSDMB protein

Description
Recombinant protein from the full-length sequence of homo sapiens gasdermin B (GSDMB), transcript variant 3 (NM_001165958), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_001165958; NP_001159430; UniProt#: Q8TAX9; GeneID: 55876;
Synonyms
GSDML; PP4052; PRO2521
Molecular Weight
47.2 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Nov 2016]

SDS-Page Image
Fig 1 : SDS-Page Image
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