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Human WNT5A protein

SKU
Name
Human WNT5A protein
Size
50 ug
Price
$398.00
Qty

Human WNT5A protein

Description
Recombinant protein from the full-length sequence of homo sapiens wingless-type MMTV integration site family member 5A (WNT5A), transcript variant 1 (NM_003392), with a His tag.
Host
Human cells
Tags
His
RefSeq Link
NM_003392; NP_003383; UniProt#: P41221; GeneID: 7474;
Synonyms
hWNT5A
Molecular Weight
42.2 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

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