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Human DICER1 protein

SKU
Name
Human DICER1 protein
Size
50 ug
Price
$398.00
Qty

Human DICER1 protein

Description
Recombinant protein from the full-length sequence of homo sapiens dicer 1, ribonuclease III (DICER1), transcript variant 1 (NM_177438), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_177438; NP_803187; UniProt#: Q9UPY3; GeneID: 23405;
Synonyms
DCR1; Dicer; Dicer1e; HERNA; K12H4.8-LIKE; MNG1; RMSE2
Molecular Weight
218.5 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010].

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