Human OGA/MGEA5 protein
Human OGA/MGEA5 protein
Description
Recombinant protein from the full-length sequence of homo sapiens meningioma expressed antigen 5 (hyaluronidase) (OGA), transcript variant 1 (NM_012215), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
Synonyms
MEA5; MGEA5; NCOAT
Molecular Weight
102.7 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008].
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