| Description | Recombinant protein from the full-length sequence of homo sapiens GLI family zinc finger 1 (GLI1), transcript variant 1 (NM_005269), with a His tag. |
| Host | Human cells |
| RefSeq Link | NM_005269; NP_005260; UniProt#: P08151; GeneID: 2735; |
| Synonyms | GLI; GLI |
| Molecular Weight | 117.7 kDa |
| Purity | >90% by SDS-PAGE gel and Coomassie Blue staining |
| Applications | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Formulation | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg) |
| Background | This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]. |
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