Human GLI1 protein

Human GLI1 protein

Human GLI1 protein

Description Recombinant protein from the full-length sequence of homo sapiens GLI family zinc finger 1 (GLI1), transcript variant 1 (NM_005269), with a His tag.
Host Human cells
RefSeq Link NM_005269; NP_005260; UniProt#: P08151; GeneID: 2735;
Synonyms GLI; GLI
Molecular Weight 117.7 kDa
Purity >90% by SDS-PAGE gel and Coomassie Blue staining
Applications Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg)
Background This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009].
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