Human EIF4B protein

Description

Recombinant protein from the full-length sequence of homo sapiens eukaryotic translation initiation factor 4B (EIF4B), transcript variant 2 (NM_001417), with a DYKDDDDK tag.

Host

Human Cells

Tags

DYKDDDDK

RefSeq Link

NM_001417; NP_001408; UniProt#: P23588; GeneID: 1975;

Synonyms

EIF-4B; PRO1843

Molecular Weight

69 kDa

Purity

>90% by SDS-PAGE gel and Coomassie Blue staining

Applications

Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Formulation

Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives

Endotoxin

Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)

Background

Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. [UniProtKB/Swiss-Prot Function]