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Human OTUD5 protein

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Name
Human OTUD5 protein
Size
50 ug
Price
$398.00
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Human OTUD5 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens OTU deubiquitinase 5 (OTUD5), transcript variant 1 (NM_017602), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_017602; NP_060072; UniProt#: Q96G74; GeneID: 55593;
Synonyms
DUBA; DUBA
Molecular Weight
60.4 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008].

SDS-Page Image
Fig 1 : SDS-Page Image
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