Human GATA4 protein

Human GATA4 protein

Human GATA4 protein

Description Recombinant protein from the full-length sequence of homo sapiens GATA binding protein 4 (GATA4), transcript variant 2 (NM_002052), with a His tag.
Host Human cells
RefSeq Link NM_002052; NP_002043; UniProt#: P43694; GeneID: 2626;
Synonyms ASD2; TACHD; TOF; VSD1
Molecular Weight 44.4 kDa
Purity >90% by SDS-PAGE gel and Coomassie Blue staining
Applications Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg)
Background This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
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