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Human FUS protein

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Name
Human FUS protein
Size
Price
$398.00
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Human FUS protein

Description
Recombinant protein from the full-length sequence of homo sapiens FUS RNA binding protein (FUS), transcript variant 1 (NM_004960), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_004960; NP_004951; UniProt#: P35637; GeneID: 2521;
Synonyms
ALS6; ETM4; FUS1; HNRNPP2; POMP75; TLS
Molecular Weight
53.2 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009].

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