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Human SULF2 protein

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Human SULF2 protein
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Human SULF2 protein

Description Recombinant protein from the full-length sequence of homo sapiens sulfatase 2 (SULF2), transcript variant 1 (NM_018837), with a His tag.
Host Human cells
RefSeq Link NM_018837; NP_061325; UniProt#: Q8IWU5; GeneID: 55959;
Synonyms HSULF-2; HSULF-2
Molecular Weight 100.3 kDa
Purity >90% by SDS-PAGE gel and Coomassie Blue staining
Applications Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg)
Background Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008].
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