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Human SULF2 protein

SKU
Name
Human SULF2 protein
Size
50 ug
Price
$398.00
Qty

Human SULF2 protein

Description
Recombinant protein from the full-length sequence of homo sapiens sulfatase 2 (SULF2), transcript variant 1 (NM_018837), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_018837; NP_061325; UniProt#: Q8IWU5; GeneID: 55959;
Synonyms
HSULF-2; HSULF-2
Molecular Weight
100.3 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008].

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