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Human EIF4E protein

SKU
Name
Human EIF4E protein
Size
50 ug
Price
$398.00
Qty

Human EIF4E protein

Description
Recombinant protein from the full-length sequence of homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1 (NM_001968), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_001968; NP_001959; UniProt#: P06730; GeneID: 1977;
Synonyms
AUTS19; CBP; eIF-4E; EIF4E1; EIF4EL1; EIF4F
Molecular Weight
25.1 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015].

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