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Human PON1 protein

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Human PON1 protein
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Human PON1 protein

Description Recombinant protein from the full-length sequence of homo sapiens paraoxonase 1 (PON1) (NM_000446), with a His tag.
Host Human cells
RefSeq Link NM_000446; NP_000437; UniProt#: P27169; GeneID: 5444;
Synonyms ESA; MVCD5; PON
Molecular Weight 39.6 kDa
Purity >90% by SDS-PAGE gel and Coomassie Blue staining
Applications Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg)
Background The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. [provided by RefSeq, Oct 2008].
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