|Description||Recombinant protein from the full-length sequence of homo sapiens integrin subunit beta 2 (ITGB2), transcript variant 1 (NM_000211), with a His tag.|
|RefSeq Link||NM_000211; NP_000202; UniProt#: P05107; GeneID: 3689;|
|Synonyms||CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7|
|Molecular Weight||82.5 kDa|
|Purity||>90% by SDS-PAGE gel and Coomassie Blue staining|
|Applications||Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!|
|Formulation||Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives|
|Endotoxin||>Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg)|
|Background||This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014].|
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