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Human ITGB2 protein

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Human ITGB2 protein
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Human ITGB2 protein

Description Recombinant protein from the full-length sequence of homo sapiens integrin subunit beta 2 (ITGB2), transcript variant 1 (NM_000211), with a His tag.
Host Human cells
RefSeq Link NM_000211; NP_000202; UniProt#: P05107; GeneID: 3689;
Synonyms CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7
Molecular Weight 82.5 kDa
Purity >90% by SDS-PAGE gel and Coomassie Blue staining
Applications Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg)
Background This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014].
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