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Human ANAPC2 protein

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Name
Human ANAPC2 protein
Size
50 ug
Price
$398.00
Qty

Human ANAPC2 protein

Description
Recombinant protein from the full-length sequence of homo sapiens anaphase promoting complex subunit 2 (ANAPC2) (NM_013366), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_013366; NP_037498; UniProt#: Q9UJX6; GeneID: 29882;
Synonyms
APC2; APC2
Molecular Weight
93.6 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq, Jul 2008].

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