Human cells

NM_002396; NP_002387; UniProt#: P23368; GeneID: 4200;

ODS1

63.4 kDa

>90% by SDS-PAGE gel and Coomassie Blue staining

Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives

Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)

This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009]