| Description | Recombinant protein from the full-length sequence of homo sapiens malic enzyme 2, NAD(+)-dependent, mitochondrial (ME2), transcript variant 1 (NM_002396), with a His tag. |
| Host | Human cells |
| RefSeq Link | NM_002396; NP_002387; UniProt#: P23368; GeneID: 4200; |
| Synonyms | ODS1 |
| Molecular Weight | 63.4 kDa |
| Purity | >90% by SDS-PAGE gel and Coomassie Blue staining |
| Applications | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Formulation | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg) |
| Background | This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009] |
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