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Human ME2 protein

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Human ME2 protein
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Human ME2 protein

Description Recombinant protein from the full-length sequence of homo sapiens malic enzyme 2, NAD(+)-dependent, mitochondrial (ME2), transcript variant 1 (NM_002396), with a His tag.
Host Human cells
RefSeq Link NM_002396; NP_002387; UniProt#: P23368; GeneID: 4200;
Synonyms ODS1
Molecular Weight 63.4 kDa
Purity >90% by SDS-PAGE gel and Coomassie Blue staining
Applications Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg)
Background This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009]
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