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Human IDUA protein

SKU
Name
Human IDUA protein
Size
50 ug
Price
$398.00
Qty

Human IDUA protein

Description
Recombinant protein from the full-length sequence of homo sapiens iduronidase, alpha-L- (IDUA), transcript variant 1 (NM_000203), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_000203; NP_000194; UniProt#: P35475; GeneID: 3425;
Synonyms
IDA; MPS1
Molecular Weight
70 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). [provided by RefSeq, Jul 2008].

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