Human cells

DYKDDDDK

NM_000203; NP_000194; UniProt#: P35475; GeneID: 3425;

IDA; MPS1

72.6 kDa

>90% by SDS-PAGE gel and Coomassie Blue staining

Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives

Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)

This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). [provided by RefSeq, Jul 2008].