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Human DNMT3A protein

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Name
Human DNMT3A protein
Size
50 ug
Price
$398.00
Qty

Human DNMT3A protein

Description
Recombinant protein from the full-length sequence of homo sapiens DNA methyltransferase 3 alpha (DNMT3A), transcript variant 1 (NM_175629), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_175629; NP_783328; UniProt#: Q9Y6K1; GeneID: 1788;
Synonyms
DNMT3A2; M.HsaIIIA; TBRS
Molecular Weight
101.7 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016].

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