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Human RNASEH2B protein

SKU
Name
Human RNASEH2B protein
Size
50 ug
Price
$398.00
Qty

Human RNASEH2B protein

Description
Recombinant protein from the full-length sequence of homo sapiens ribonuclease H2 subunit B (RNASEH2B), transcript variant 2 (NM_001142279), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_001142279; NP_001135751; UniProt#: G3XAJ1; GeneID: 79621;
Synonyms
AGS2; DLEU8
Molecular Weight
28.8 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2). [provided by RefSeq, Nov 2008].

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