|Description||Recombinant protein of the extracellular domain (Gln16- Pro162) of Homo sapiens triggering receptor expressed on myeloid cells like 1 (TREML1/TLT-1), transcript variant 1 (NM_178174), with a polyhistidine tag.|
|RefSeq Link||NM_178174; NP_835468 ; UniProt#: Q86YW5; GeneID: 340205;|
|Synonyms||dJ238O23.3; GLTL1825; PRO3438; TLT-1; TLT1|
|Molecular Weight||18 kDa|
|Purity||>90% by SDS-PAGE gel and Coomassie Blue staining|
|Applications||Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!|
|Formulation||Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives|
|Endotoxin||>Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg)|
|Background||This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012].|
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