×
Login

Human TNFRSF1B Protein

SKU
Name
Human TNFRSF1B Protein
Size
50 ug
Price
$398.00
Qty

Human TNFRSF1B Protein

Description
Recombinant protein from the extracellular domain (Leu23-Asp257) of homo sapiens TNF receptor superfamily member 1B (TNFRSF1B) (NM_001066), with a human IgG1 Fc tag.
Host
Human cells
Tags
Human IgG1 Fc
Source
CI1000323
RefSeq Link
NM_001066; NP_001057; UniProt#: P20333; GeneID: 7133;
Synonyms
CD120b; p75; p75TNFR; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80
Molecular Weight
51.2 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008].

SDS-Page Image
Fig 1 : SDS-Page Image
Contact Us
View Storefront

Related Products

Customers who come to this page are also interested in the following products:


There's no citations at this moment.


There's no FAQs at this moment.


There's no reviews at this moment.