×
Login

KRAS proto-oncogene, GTPase (KRAS)

Reference Link
UniProt:
Accession:
GeneID:

Background

The Kirsten Ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. The KRAS gene provides instructions for making a protein called K-Ras, part of the RAS/MAPK pathway. The protein relays signals from outside the cell to the cell's nucleus. These signals instruct the cell to grow and divide (proliferate) or to mature and take on specialized functions (differentiate).

KRAS acts as a molecular on/off switch, using protein dynamics. Once it is allosterically activated, it recruits and activates proteins necessary for the propagation of growth factors, as well as other cell signaling receptors like c-Raf and PI 3-kinase.

EUPROTEIN Offering

EUPROTEIN has developed and validated KRAS proteins that could be used in the studies of oncogene drug development and/or immunoassay development.

Recombinant KRAS Protein
Human KRAS protein EP8846610
Recombinant KRAS Protein
Human KRAS protein EPY203181
KRAS G12a mutant protein
KRAS G12a mutant protein EPY203187
KRAS G12C Mutant Protein
KRAS G12C Mutant Protein EPY203185
KRAS G12D Mutant Protein
KRAS G12D Mutant Protein EPY203182
KRAS G12S Mutant Protein
KRAS G12S Mutant Protein EPY203186
KRAS G12V Mutant Protein
KRAS G12V Mutant Protein EPY203183
KRAS G13D Mutant Protein
KRAS G13D Mutant Protein EPY203184

If you need help expressing KRAS proteins or generating antibodies against them, please submit your inquiry by clicking the button below. Our service representative will get back to you promptly to discuss your project needs.

Submit Your Inquiry